There have been several significant First Ladies in Black history who have made remarkable contributions to society and helped shape the course of American history. Here are a few notable examples:

1. Michelle Obama: Michelle Obama, wife of the 44th President of the United States, Barack Obama, served as First Lady from 2009 to 2017. She used her platform to advocate for various causes, including promoting healthy eating and physical activity, supporting military families, and advocating for education. Michelle Obama also launched initiatives like the Let's Move! campaign to combat childhood obesity and the Reach Higher initiative to encourage young people to pursue higher education.

2. Eleanor Roosevelt: Although not a Black woman herself, Eleanor Roosevelt was a pioneering First Lady who worked closely with prominent African American leaders, such as civil rights activist Mary McLeod Bethune, and advocated for racial equality. She used her position to campaign for anti-lynching legislation and desegregation of the armed forces, among other civil rights issues.

3. Coretta Scott King: Coretta Scott King, the wife of civil rights leader Martin Luther King Jr., played a crucial role in the civil rights movement and continued her husband's work after his assassination. As First Lady of the civil rights movement, Coretta Scott King advocated for racial and social justice, women's rights, and LGBT rights. She founded the Martin Luther King Jr. Center for Nonviolent Social Change and worked tirelessly to promote her husband's legacy.

These are just a few examples of the remarkable First Ladies in Black history who have made lasting impacts on society and have left a legacy of service, activism, and advocacy.